Best Supplements for Men Over 40 – The Complete Guide to Supplements for Guys Over 40

the best supplements for men over 40 years old
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For men over 40, taking the correct dietary supplements can make the difference from beginning to age quickly or retaining youth and vibrancy.

Did you know that with the right supplement plan, as well as proper exercise and a healthy diet, men over 40 can still have an aesthetic body? Just look at The Rock, John Cena, or any other 40+ man with an incredible physique!

The supplements for men over 40 in this article will help you feel younger and look younger, well past your 40s!

Keep reading below to see the best supplements for men over 40!

The Best Supplements for Guys Over 40

the best workout supplements for men over 40

In my opinion, the best supplements for men over 40 are:

  1. A Multivitamin Supplement
  2. Fish Oil
  3. Calcium
  4. Zinc
  5. Vitamin C
  6. Melatonin
  7. Magnesium
  8. Vitamin D
  9. Turmeric
  10. Maca Root
  11. Ginger
  12. Collagen and Hyaluronic Acid

Check out the benefits of them and why they are important:

Multivitamin Supplements for Guys Over 40

The main reason that men over 40, or anyone, should take dietary supplements, is to provide nutrients that your diet is lacking.

Some people have nutrient deficiencies due to an illness or their lifestyle, and dietary supplements can adequately fill in this void. According to a study published in the Nutrition Journal,

“A balanced and varied diet is the best source of essential vitamins and minerals; however, nutrient deficiencies occur, including in populations with bountiful food supplies and the means to procure nutrient-rich foods. For example, the typical American diet bears little resemblance to what experts recommend for fruit, vegetables, and whole grains, which serve as important sources of an array of vitamins and minerals.”

Due to that, I believe the best supplement for men over 40 is a simple multivitamin. A multivitamin supplement can help fill many of the nutritional gaps you are having problems with.

According to the same study published in the Nutrition Journal,

“In addition to the utility of multivitamins (MVMs) for filling in relatively small but critical nutritional gaps, which may help prevent conditions such as anemia, neural tube defects, and osteoporosis, some evidence supports possible benefits of MVM supplementation with regard to cancer prevention (particularly in men) and prevention or delay of cataract, as well as some aspects of cognitive performance… The potential benefits of MVM supplements likely outweigh any risk in the general population and may be particularly beneficial for older people.”

If you are interested in using a multivitamin which will cover many nutrition deficiencies, I suggest:

Rainbow Light - 50+ Mini-Tablet Food-Based Multivitamin - Age-defense Formula Probiotic and Antioxidant Formula; Vitamins and Minerals Support Immune, Heart, Skin, Eye, Bone and Prostate - 180 Tablets
  • WHOLE-BODY SUPPORT: Vitamins and minerals support immune, heart, skin, eye, bone, and prostate...
  • NUTRITION: Concentrated superfoods, vegetables, and vitamin B-complex for added nutrition
  • PROBIOTIC DIGESTIVE SUPPORT: Probiotics and plant-sourced enzymes support digestive health
  • EASY-TO-SWALLOW: Mini-tablets are easy to swallow
  • ALLERGY-FRIENDLY Contains NO: gluten, wheat, milk, tree nuts, peanuts, eggs, fish or shellfish.

Another good option is the Alpha Wolf Nutrition multivitamin.

Fish Oil Supplements for Men Over 40

Omega-3 fatty acids (such as from fish oil supplements) help slow down the aging process and keep your body looking youthful, which is why they are one of the best supplements for men over 40. Also, omega-3 fatty acid supplements can help reduce the incidence of dementia or Alzheimer’s Disease.

According to a study published in Nature Reviews Neurology,

“Long-chain omega-3 fatty acids could have neuroprotective properties against dementia.”

Furthermore, fish oil is one of the best supplements for muscle gain and weight loss, and it is particularly one of the best supplements for guys over 40looking to preserve their lean muscle mass. According to a study published in The American Journal of Clinical Nutrition,

“Fish oil-derived n-3 PUFA therapy slows the normal decline in muscle mass and function in older adults and should be considered a therapeutic approach for preventing sarcopenia and maintaining physical independence in older adults.”

In my opinion, the best fish oil supplement you should try is Utzy Naturals U-Omega:

Omega 3 Fish Oil | Natural Triglyceride Fish Oil | 120 Softgels | Lemon-Lime Flavor | Pharmaceutical Grade | 3rd Party Tested
  • FRESH & PURE – Our premium fish oil is made with the finest quality and purity standards to create...
  • ETHICALLY SOURCED - High absorption fish oil
  • EASY TO CONSUME - We’ve even added a hint of natural lemon flavor to make the perfect blend of...
  • PREMIUM QUALITY - Made in the USA in a cGMP manufacturing facility

Calcium Supplements for Guys Over 40

Calcium is crucial for maintaining bone health, amongst other health benefits. As you age, your bones begin to weaken, and you need proper calcium intake to retain their strength. Although the majority of bone health is related to calcium intake in younger years, maintaining adequate calcium intake is necessary for preventing osteoporosis and other age-related bone issues.

If you are serious about improving your bone density as a man over 40, the calcium supplement I suggest is:

New Chapter Calcium Supplement – Bone Strength Organic Plant Calcium with Vitamin K2 + D3 + Magnesium, Vegetarian, Gluten Free - 120 count (40 day supply)
  • BONE STRENGTH: Protects against bone loss and promotes bone density & joint mobility*
  • ORGANIC CALCIUM: USDA Organic plant-based calcium from sustainably harvested Red Marine Algae
  • Formulated for Absorption: Expertly formulated with Vitamin D3 for better absorption, Vitamin K2 to...
  • Slim, easy-to-swallow tablets with slow & steady release
  • USDA Organic, Non-GMO Project Verified, 100% Vegetarian, Kosher, Certified Gluten Free by NSF,...

Vitamin C and Zinc for Men Over 40

I decided to group these two supplements together because they both are so intricately involved in maintaining your immune system as a man over 40.

I take zinc before bed each night, and I consistently take a Vitamin C supplement all year round (even though I am not over 40 years old yet). Both of these nutrients help in optimizing the performance of white blood cells.

According to one study which was published by The Nutrition Society,

“Zn is an essential trace element for all organisms. In human subjects body growth and development is strictly dependent on Zn. The nervous, reproductive and immune systems are particularly influenced by Zn deficiency, as well as by increased levels of Zn.”

Likewise, as stated in another research study,

“Several cells of the immune system can indeed accumulate vitamin C and need the vitamin to perform their task, especially phagocytes and t-cells. Thus a vitamin C deficiency results in a reduced resistance against certain pathogens whilst a higher supply enhances several immune system parameters.”

If you would like to try a supplement which contains both zinc and Vitamin C for improving your immune system, I suggest:

Vitamin C 1000mg Complex with L-Lysine 500mg, Zinc 12mg, Bioflavonoids 300mg. Doctor Formulated Magnesium Stearate Free Supplements for Healthy Immune System Support.(1)
  • Doctor Formulated Supplements support healthy Immune System - with Zinc, l-lysine and bioflavonoids.
  • Each bottle contains 6o vegetarian capsules. Suggested use 2 capsules a day.
  • Bioflavonoids increase absorption of vitamin C and are a powerful antioxidant.
  • Antioxidant - Vitamin C is required for production and maintenance of collagen, and bioflavonoids...
  • With L-Lysine to support healthy lips. Magnesium Stearate Free.

Especially for men over forty, taking supplements to enhance your immune system can help ward off diseases or illnesses!

Melatonin for Guys Over 40

There are several benefits of taking melatonin supplements for guys over 40 years old.

The main benefit of taking melatonin is that it can help you sleep better each night. In fact, taking a melatonin supplement can help you lose weight overnight because you will sleep better and have an increased metabolism.

Furthermore, another benefit of melatonin for men over forty is that it reduces the risk of several different types of cancer. According to a study published in the Journal of Clinical Oncology,

“Melatonin, the chief secretory product of the pineal gland, is a direct free radical scavenger, an indirect antioxidant, as well as an important immunomodulatory agent. In both in vitro and in vivo investigations, melatonin protected healthy cells from radiation-induced and chemotherapeutic drug–induced toxicity. Furthermore, several clinical studies have demonstrated the potential of melatonin, either alone or in combination with traditional therapy, to yield a favorable efficacy to toxicity ratio in the treatment of human cancers.”

In my opinion, the best melatonin supplement you can purchase is:

Magnesium Supplements for Men Over 40

best supplement options for men over 40Magnesium is one of the best supplements for guys over 40 and it is one of the most neglected nutrients overall. Magnesium is one of seven macro-minerals that’s abundant in your body, and it’s also a mineral that your body can’t function without.

Magnesium plays a huge role in coordinating over 300 enzymatic reactions within the human body, such as nerve impulse transmission, food metabolism, cell stabilization, DNA synthesis, and protein synthesis, and the synthesis of fatty acids and proteins.

Magnesium is also responsible for keeping your bones healthy, keeping your muscles healthy (which includes your heart), it relieves anxiety, it plays a vital role in exercise performance, and more!

As you can see, magnesium is a critical mineral for your body.

Some of the signs of magnesium deficiency to watch out for are:

  • Muscle cramps
  • Seizures
  • Irregular heart rhythms (arrhythmia)
  • Cramps
  • Back disorders
  • Numbness and tingling

Eating a healthy diet can provide adequate amounts of magnesium for your body, but you need to know where your food comes from.

Fortunately, you can easily get magnesium supplements in Australia, the United States, Europe, or wherever else you are living.

If you are interested in buying a magnesium supplement, the supplement I suggest is:

BioEmblem Triple Magnesium Complex | 300mg of Magnesium Glycinate, Malate, & Citrate for Muscle Relaxation, Sleep, Calm, & Energy | High Absorption | Vegan, Non-GMO | 90 Capsules
  • SUPPORTS RELAXATION, CALMNESS & IMPROVED SLEEP: Magnesium, especially in mag...
  • PROMOTES HEART HEALTH AND ENERGY PRODUCTION: As a cofactor in hundreds of enzyme...
  • BONE DENSITY & MUSCLE RECOVERY: Studies have shown that magnesium helps regulate...
  • 3RD PARTY TESTED & BIOEMBLEM QUALITY: BioEmblem Triple Magnesium Complex is made in...

Vitamin D for Men Over 40

Vitamin D, also known as the “sunshine vitamin,” is an essential nutrient for almost all bodily functions, and it is definitely one of the best supplements for men over 40. This key vitamin has not only been shown to increase immune system health and improve and prevent depression, but has also been extensively studied for its ability to prevent degenerative diseases such as osteoporosis, cancer, and diabetes.

As stated by a study published in a study by The Journal of the American Board of Family Medicine,

“Vitamin D is a fat-soluble vitamin that plays an important role in bone metabolism and seems to have some anti-inflammatory and immune-modulating properties.”

Furthermore, according to a study published in The American Journal of Clinical Nutrition,

“Very few foods naturally contain vitamin D, and foods that are fortified with vitamin D are often inadequate to satisfy either a child’s or an adult’s vitamin D requirement. Vitamin D deficiency causes rickets in children and will precipitate and exacerbate osteopenia, osteoporosis, and fractures in adults. Vitamin D deficiency has been associated with increased risk of common cancers, autoimmune diseases, hypertension, and infectious diseases.”

Unfortunately, Vitamin D deficiency is quite common due to factors such as inadequate sun exposure, and not enough rich Vitamin D foods in the diet. Exercising outdoors can drastically help Vitamin D absorption, but sometimes even that is not enough.

If you are going to use a Vitamin D supplement, you should use a Vitamin D3 supplement that also contains Vitamin K2. D3 can cause issues with blood clotting, and the role of K2 is to promote blood flow through the veins so this is not an issue.

Here is a great Vitamin D supplement for men over 40:

NutriFlair Plant-Based Vitamin K2 (as Mk7) with D3 (5000iu/125mcg) Vitamins Plus BioPerine, 90 Capsules
  • 100% Plant-based - Made with Plant-based K2 from Chickpeas and D3 from Lichen - All Natural,...
  • 100 mcg of Vitamin K2 per capsule and 125 mcg Vitamin D3 per capsule. Also enhcnced with Bioperine...
  • This 2-in-one K2 + D3 supplement provides incredible health benefits for heart and bone support*
  • Tested & Trusted Ingredients - Our non-gmo, soy-free, gluten-free and dairy-free, D3 Supplement with...
  • Trusted Brand - Satisfaction Assured. If our Vitamins K2 + D3 supplement does not bring noticeable...

Turmeric Supplements for Guys Over 40

Turmeric is one of the staples of Ayurvedic medicine and without a doubt one of the most powerful health products on the planet. Turmeric has been used in Ayurvedic medicine for literally thousands of years, and academic research has recently begun proving the innumerable benefits of this product!

According to one study,

“For the last few decades, extensive work has been done to establish the biological activities and pharmacological actions of turmeric and its extracts. Curcumin (diferuloylmethane), the main yellow bio-active component of turmeric has been shown to have a wide spectrum of biological actions. These include its anti-inflammatory, antioxidant, anti-carcinogenic, anti-mutagenic, anticoagulant, anti-fertility, anti-diabetic, antibacterial, anti-fungal, antiprotozoal, antiviral, antifibrotic, antivenom, anti-ulcer, hypotensive and hypocholesteremic activities.”

Most notably, turmeric is great for reducing inflammation throughout the body. According to a study published in the International Journal of Pharmaceutical Sciences and Research,

“Inflammation is generally regarded as a source of many health challenges. Turmeric is an excellent anti-inflammatory herb; easing conditions such as bursitis, arthritis, back pain etc and plays an important role in inflammation. The anti-inflammatory action of turmeric includes lowering histamine levels and increasing the production of natural cortisone by adrenal glands. “

For men over 40 who are dealing with joint pain, according to a study which was published in Holistic Nursing Practice,

“Researchers concluded that curcumin extracts are as effective as ibuprofen for the treatment of pain in knee osteoarthritis (OA).”

Furthermore, turmeric is know for its ability to burn fat. Unlike other fat burners or diet pills, turmeric helps you lose body fat long-term because it promotes overall health and can increase your basal metabolic rate by stimulating a healthy body.

Lastly, one of the most specific health benefits of turmeric for men is that taking a turmeric supplement can help with sexual health (erectile function). According to a study on the comparison of a turmeric supplement and the erectile dysfunction medicine tadalafil (Cialis) that was published in Andrologia,

“Novel Curcumin Derivative (NCD) or its combination with tadalafil showed significant superiority and more prolonged duration of action. In conclusion, a tendency was observed that curcumin (CURC) and NCD have high efficacy and more prolonged duration of action in enhancing erectile function.”

Turmeric curcumin is most commonly combined with black pepper in order to enhance the absorption rate of curcumin, and to increase its healing properties!

In my opinion, using turmeric supplements is one of the simplest health tips for men that can make a substantial impact!

If you would like to purchase a turmeric supplement for yourself, I suggest you try Nuvana Turmeric Curcumin with Bioperine and Ginger. I use this product myself, and I am confident in suggesting it to you. Taking a turmeric supplement that also contains Bioperine (black pepper) and ginger enhances the properties of turmeric and helps it absorb better!

Sustain Turmeric Curcumin, Boswellia & Ginger with BioPerine | Pain Relief, Joint Support, Anti-Inflammatory, Antioxidant Supplement with 95% Standardized Curcuminoids - 60 Vegan Capsules
  • FULL BODY BENEFITS - Our powerful, all-natural formula of curcumin, boswellia and ginger acts to...
  • A BETTER BLEND - Studies have shown that the combined effect of Sustain’s unique ingredients...
  • PREMIUM POTENCY - Sustain uses BioPerine black pepper extract to allow for maximum absorption,...
  • MADE IN THE USA - All Nuvana products are lab-tested & produced in a state-of-the-art facility...
  • A BRAND YOU CAN TRUST - At Nuvana, we proudly stand behind the safety and efficacy of our products....

Maca Root Supplements for Men Over 40

Maca Root is an excellent supplement for men over 40 because it can assist with problems with libido, erectile dysfunction, and general aging. According to a study published in Andrologia,

“In conclusion, our data support a small but significant effect of Maca supplementation on subjective perception of general and sexual well-being in adult patients with mild ED.”

Although the research is not conclusive on whether or not maca root supplements can increase testosterone or have effects on other important male hormones, it is evident that maca root has beneficial effects for men over 40.

If you would like to purchase a maca root supplement, my suggestion is:

Maca Root Capsules | 120 Pills | High Potency Extract for Men and Women | Non-GMO and Gluten Free Formula | by Horbaach
  • MACA CAPSULES: Experience the power of natural Maca Root and its incredible nutrients
  • OPTIMAL ABSORPTION: Delivers the equivalent of 3200 mg of Peruvian Maca in a Quick-Release capsule
  • SUPER CONCENTRATED: Our Peruvian Maca is expertly sourced from a potent, super concentrated extract
  • HORBAACH MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
  • NATURALLY FREE OF: Gluten, Wheat, Yeast, Milk, Lactose, Soy, Artificial Color & Flavoring & NON-GMO

Alternatively, you could purchase a superfood powder that contains maca root and other beneficial superfoods, such as Your Super Muscle Power.

Ginger Supplements for Guys Over 40

best ginger supplement for men over 40

Ginger is a foundational herb in many traditional medicines. Ginger is classified as one of the safest remedies in the world, and the list of health benefits of ginger is vast. As stated by a study published in the Hawaii Medical Journal,

“Ginger has been used safely for thousands of years in cooking, and medicinally in folk and home remedies. Advanced technology enables the validation of these traditional experiences.”

Gingerol is an oil that is found in ginger, and it is not only an antioxidant but also a potent anti-cancer agent. According to researchers, not only do they prevent cancer, but they also safely destroy cancerous cells without any known side effects.

Studies have routinely shown that cancers that can be cured or positively impacted by ginger are prostate cancer, colon, skin, ovarian, and breast cancer.

According to a study published in Food and Chemical Toxicology,

“Some pungent constituents present in ginger and other zingiberaceous plants have potent antioxidant and anti-inflammatory activities, and some of them exhibit cancer preventive activity in experimental carcinogenesis. The anticancer properties of ginger are attributed to the presence of certain pungent vallinoids, viz. [6]-gingerol and [6]-paradol, as well as some other constituents like shogaols, zingerone etc.”

Ginger, or any other antioxidant such as this, is best used as preventative medicine, being routinely used daily to ward off any attacks against your body.

Along with that, harmful stomach acids that can contribute to ulcer formation can be very well neutralized with ginger. As claimed in a study published by the Journal of Ethnopharmacology,

“6-Gingerol, the pungent principle, at 100 mg/kg significantly inhibited gastric lesions by 54.5%. These results suggest that zingiberene, the terpenoid, and 6-gingerol are important constituents in stomachic medications containing ginger.”

Men who have high-stress jobs and who are at high risk of ulcers should strongly consider using a ginger supplement!

There are several other health benefits of ginger supplements for men over 40, but these are just a couple.

If you would like to try a ginger supplement, my suggestion is:

Herbal Secrets Ginger Root 550 Mg 250 Capsules (Non-GMO)- Helps to Reduce Nausea * Supports Upset Stomach*
  • OPTIMAL DOSE FOR SIMPLE SUPPLEMENTATION Each of our ginger pills provides 550 milligrams of pure...
  • A TRULY NATURAL SOLUTION Unlike other ginger tablets on the market, our ginger root capsules are...
  • EASY TO SWALLOW Our ginger root pills come in a capsule form, so they're very easy to take, even if...
  • At Herbal Secrets we believe in what a wise man once said, "All that man needs for health and...
  • All Herbal Secrets products are proudly made in USA in accordance with Good Manufacturing Practices...

Collagen and Hyaluronic Acid Supplements for Men Over 40

There are several benefits of collagen and hyaluronic acid supplements for men over 40, most notably that they can help reduce joint pain and increase youthfulness through the stimulation of collagen production.

Collagen is a type of protein that is found in fibrous tissues such as skin, tendons and ligaments, cartilage, blood vessels, and bone.

As stated by a study published in Current Medical Research and Opinion,

“This was the first clinical trial of 24-weeks duration to show improvement of joint pain in athletes who were treated with the dietary supplement collagen hydrolysate. The results of this study have implications for the use of collagen hydrolysate to support joint health and possibly reduce the risk of joint deterioration in a high-risk group.

Furthermore, according to a study published in Clinical Interventions in Aging,

“This study provides preliminary data suggesting that dietary supplementation with BCC (BioCell Collagen) elicits several physiological events which can be harnessed to counteract natural photoaging processes to reduce visible aging signs in the human face. A controlled study is necessary to verify these observations.”

Taking collagen and hyaluronic acid supplements is a great way to naturally reduce joint pain and have a more youthful appearance for men over 40!

If you would like to try a collagen and hyaluronic acid supplement, my suggestion is:

NOW Supplements, BioCell Collagen® Hydrolyzed Type II, Clinically Validated, 120 Veg Capsules
  • BioCell Collagen is a versatile nutritional supplement that supports both joint health and moisture...
  • Joint Mobility and Comfort*
  • Promotes Healthy Skin*
  • Clinically Validated
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing...

Concluding Thoughts – The Most Important Supplements for Men Over 40

If you are a man over 40 looking for the best supplements to improve your health and help you remain youthful as long as possible, I am confident that the best supplements for men over 40 are listed above!

Read Next: How to Become Fit After 50


Adam Kemp
Hello! My name is Adam Kemp. I am a professional basketball player and an ISSA Certified Personal Trainer. In 2014 I graduated from Marist College with a B.A. in Communications, and in 2022 I completed my Master's of Science in Nutrition Education at American University. Additionally, for the last eight years, I have played professional basketball in Europe. I am also an ISSA Certified Personal Trainer. The health and fitness tips you can find throughout the articles I have written include information I have learned throughout my basketball career, academic studies, and my own personal research. If you would like to learn more about my life, please take a moment to follow me on Instagram and Twitter.

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